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Opis: Anti-Itgam Rat Monoclonal Antibody [clone: M1/70] (PE (Phycoerythrin))
Numer katalogowy: PRSI98-645
j.m.: 1 * 0,1 mg
Producent: ProSci Inc.


Opis: CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
Numer katalogowy: BNCB1053-100
j.m.: 1 * 100 µl
Producent: Biotium


Opis: CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin αM combines with the Integrin β2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin αM/β2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. The protein CD11b has been implicated in the various adhesion-related interactions of cells such as monocytes, macrophages, natural killer (NK) cells, and granulocytes. It is part of a heterodimer that consists of CD11b and CD18. It also modulates the uptake of complement-coated particles within the cell. It is commonly used as a microglial marker in tissues derived from the nervous system.
Numer katalogowy: BNUB0720-500
j.m.: 1 * 500 µl
Producent: Biotium


Opis: CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin αM combines with the Integrin β2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin αM/β2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. The protein CD11b has been implicated in the various adhesion-related interactions of cells such as monocytes, macrophages, natural killer (NK) cells, and granulocytes. It is part of a heterodimer that consists of CD11b and CD18. It also modulates the uptake of complement-coated particles within the cell. It is commonly used as a microglial marker in tissues derived from the nervous system.
Numer katalogowy: BNC040720-100
j.m.: 1 * 100 µl
Producent: Biotium


Opis: Rat monoclonal [M1/70] antibody to CD11b (PE) for flow cytometry with samples derived from human, mouse, rabbit and non-human primates.
Numer katalogowy: ANTIA85797-100
j.m.: 1 * 100 µG
Producent: ANTIBODIES.COM

New Product


Opis: CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin αM combines with the Integrin β2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin αM/β2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. The protein CD11b has been implicated in the various adhesion-related interactions of cells such as monocytes, macrophages, natural killer (NK) cells, and granulocytes. It is part of a heterodimer that consists of CD11b and CD18. It also modulates the uptake of complement-coated particles within the cell. It is commonly used as a microglial marker in tissues derived from the nervous system.
Numer katalogowy: BNC400720-100
j.m.: 1 * 100 µl
Producent: Biotium


Opis: Anti-CD11b is useful for Immunoprecipitation, immunochemistry, and Flow Cytometry using mouse spleen cells, or an appropriate cell type (where indicated). Researchers should determine optimal titers for applications that are not stated.
Numer katalogowy: ROCK200-508-N79
j.m.: 1 * 200 µG
Producent: Rockland Immunochemicals


Opis: The M1/70 antibody reacts with human and mouse CD11b, also known as integrin alpha M. This 165-170 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha M (CD11b) assembles with Integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling through ICAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.
Numer katalogowy: 60-0112-U100
j.m.: 1 * 100 µG
Producent: Tonbo Biosciences


Opis: The M1/70 monoclonal antibody specifically reacts with the 170 kDa alpha M integrin chain of mouse CD11b from the Mac-1 integrin (CD11b/CD18). Mac-1 binds to C3bi, CD54 (ICAM-1), and fibrinogen, and it is expressed by granulocytes, macrophages, NK cells, myeloid-derived dendritic cells, microglia, activated lymphocytes, and mouse B-1 cells. The expression is up-regulated on activated neutrophils at the same time that L-selectin is shed from the cell surface. The M1/70 antibody is used for the detection of monocytes, granulocytes, and a subset of natural killer cells in human peripheral blood.M1/70 blocks C3bi binding and cell adherence, but not cell-mediated lysis and it cross-reacts with human CD11b.
Numer katalogowy: PRSI76-120
j.m.: 1 * 0,5 mg
Producent: ProSci Inc.


Opis: Anti-Itgam Rat Monoclonal Antibody [clone: M1/70] (APC (Allophycocyanin)-Cy7®)
Numer katalogowy: PRSI98-651
j.m.: 1 * 0,1 mg
Producent: ProSci Inc.


Opis: Alexa Fluor® 594 Rat monoclonal [M1/70] to CD11b.
Numer katalogowy: ABCAAB312914-10UL
j.m.: 1 * 10 µl
Producent: Abcam


Opis: Anti-CD11b Rat Monoclonal Antibody [clone: M1/70]
Numer katalogowy: ANTIA86819-100
j.m.: 1 * 100 µG
Producent: ANTIBODIES.COM

New Product


Opis: Mouse monoclonal antibody raised against influenza B virus Matrix protein M1.
Numer katalogowy: ABNOMAB3152
j.m.: 1 * 200 µG
Producent: Abnova


Opis: Prostokątne odważniki wykonane z żeliwa (gęstość 7,2 g/cm³).
Numer katalogowy: 611-8298
j.m.: 1 * 1 SZT
Producent: VWR Collection


Opis: The M1/70 antibody reacts with human and mouse CD11b, also known as integrin alpha M. This 165-170 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha M (CD11b) assembles with Integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling through ICAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.
Numer katalogowy: 35-0112-U100
j.m.: 1 * 100 µG
Producent: Tonbo Biosciences


Opis: Anti-Itgam Rat Monoclonal Antibody [clone: M1/70] (PE (Phycoerythrin)-Cy7®)
Numer katalogowy: PRSI98-650
j.m.: 1 * 0,1 mg
Producent: ProSci Inc.