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Metylosiarczan 5-metylofenazyny, dark yellow powder

Dostawca: MP Biomedicals
Uwaga

Synonim: PMS, 5-Methylphenazin-5-ium methyl sulphate, Phenazine methosulphate, Phenazine methylsulphate

0210095510 0210095501 0210095505
ICNA0210095510EA 1950 PLN
ICNA0210095510 ICNA0210095501 ICNA0210095505
Metylosiarczan 5-metylofenazyny, dark yellow powder
Metylosiarczan 5-metylofenazyny

Phenazine methosulfate is an electron acceptor and carrier in enzyme systems. The oxidised form is yellow and the reduced form is colourless.


Phenazine methosulfate is used in tyrosine transaminase test and for enzymic determination of ethanol in blood by the colorimetric micromethod. Used with ascorbic acid to determine nitric oxide reductase activity. Since the reduced PMS is easily oxidised by oxygen, it is used in assays as an electron carrier between enzymes and oxygen, cytochrome c, indophenols, or tetrazolium salts. The reduced PMS is used as an electron donor to reduce cytochrome c or in photosynthetic experiments. Usage of PMS for detection of specific dehydrogenases has been reported.


PMS is reduced by flavoproteins such as succinic dehydrogenase. PMS is reduced non-enzymatically by NADH and NADPH. PMS is also reduced by dithionite, sodium borohydride, ascorbic acid, reduced ubiquinones, and reduced vitamin K. PMS reacts with sulphhydryl groups including those of enzymes.


Soluble in water(800 mg/4 ml), ethanol,methanol (5% w/v); insoluble in benzene, diethyl ether.

Formuła: C₁₄H₁₄N₂O₄S
MW: 306.34 g/mol
Temp. topnienia: 198
Temperatura przechowywania: Zamra·arka
Numer MDL: MFCD00011923
Numer CAS: 299-11-6
Numer WE (dawny EINECS): 206-072-1
Klasyfikacja Merck : 12,06185

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