Drukuj

Anti-PTPRC Mouse Monoclonal Antibody (CF770) [clone: 2B11 PD7/26]

Dostawca: Biotium
BNC700745-500 BNC700745-100
BNC700745-500EA 2860 PLN
BNC700745-500 BNC700745-100
Anti-PTPRC Mouse Monoclonal Antibody (CF770) [clone: 2B11 PD7/26]
Przeciwciała
Recognizes the CD45 leukocyte common antigen (LCA) family which is comprised of at least four isoforms of membrane glycoproteins (220, 205, 190, 180 kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant non-hematopoietic tissues. The intracellular portions of these molecules have protein phosphatase activity and are involved in regulation of transmembrane signals. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms. A positive result with this MAb is highly indicative of lymphoid or myeloid origin. Certain types of lymphoid neoplasms may lack CD45 (Hodgkin lymphoma, some T-cell lymphomas, and some leukemias) so its absence does not rule out a hematolymphoid tumor. This antibody is expressed almost exclusively by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes as well as plasma cell precursors.

Type: Primary
Antigen: PTPRC
Clonality: Monoclonal
Clone: 2B11 PD7/26
Conjugation: CF770
Epitope:
Host: Mouse
Isotype: IgG
Reactivity: Dog, Human
Zobacz ceny

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Więcej About VWR