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Losartan potassium ≥98%, crystalline

Dostawca: Cayman Chemical

Synonim: MK-954, DUP-753, 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl]imidazole-5-methanol Potassium Salt, (1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol, potassium salt

10006594-10 10006594-100 10006594-50 10006594-500
CAYM10006594-10EA 133 PLN
CAYM10006594-10 CAYM10006594-100 CAYM10006594-50 CAYM10006594-500
Losartan potassium ≥98%, crystalline
Losartan potassium

Angiotensin II is a hormone that plays an important role in regulating blood pressure.


  • Synonyms: DuP-753; MK 954


Elevated levels of angiotensin II are implicated in inducing and maintaining hypertension, and also in the development of atherosclerosis. Both of these effects are mediated by the angiotensin II type 1 (AT1) receptor. Losartan is an AT1 receptor antagonist with a Ki value of 5 to 20 nM. It has an attenuating effect on vein graft atherosclerosis in rabbits and effectively reduces arterial blood pressure in rats. In humans, losartan controls hypertension while protecting renal function.

Formuła: C₂₂H₂₃ClN₆O
MW: 461.01 g/mol
Numer MDL: MFCD02092704
Numer CAS: 124750-99-8

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Wyniki testów specyfikacyjnych

Purity ≥95%
Stability ≥2 years at −20 °C
Form A Crystaline Solid


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