Wyszukano: Tyrphostin AG-126

Numer katalogowy: (APOSBISN0202-5MG)

Producent: Apollo Scientific

Opis: MAPK/ERK Signalling Pathway

j.m.: 1 * 5 mg

Wyprzedaż

Producent: ENZO LIFE SCIENCES

Opis: AG-126 prevents lipopolysaccharide-induced lethal toxicity (septic shock) in mice. Administered at 1.5 mg/mouse, it reduced LPS-induced lethal toxicity from 95% to 10%. AG-126 greatly reduces LPS-induced tyrosine phosphorylation of p42MAPK in murine peritoneal macrophages at 50 µM. EGFR, Her-2/neu receptor or PDGF-R are not inhibited at 100 µM. Inhibits tyrosine kinase-dependent B cell receptor signaling.