Wyszukano: Rapamycin

Producent: ENZO LIFE SCIENCES

Opis: Macrocyclic-triene antibiotic possessing potent immunosuppressant activity. It forms a complex with FKBP12 that binds to an effector, thus inhibiting IL-2 and other growth promoting lymphokines. The effectors were identified as FRAP (FKBP12 rapamycin-associated protein) and RAFT1 (rapamycin and KFBP12 target). rapamycin/FKBP complex does not inhibit FRAP PI 4-kinase activity, but does inhibit FRAP autophosphorylation. rapamycin induces inhibition of p70^s6k, p33^cdk2 and p34^cdc2. Selectively blocks signaling leading to the activation of p70/85 S6 kinase. Enhances apoptosis. Activator of autophagy both<i> in vitro</i> and <i>in vivo</i>.

Producent: Apollo Scientific

Opis: Macrocyclic triene antibiotic.

Producent: Thermo Fisher Scientific

Opis: Rapamycin ≥99%

MSDS Certyfikaty

Producent: MP Biomedicals

Opis: Rapamycin binds to and inhibits the molecular target of Rapamycin (mTOR). It forms a complex with FKBP12 that binds to and inhibits the molecular target of Rapamycin (mTOR). Rapamycin is a potent immunosuppressant and has anticancer activity.