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Opis: Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
Numer katalogowy: BOSSBS-7090R-HRP
j.m.: 1 * 100 µl
Producent: Bioss


Opis: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Numer katalogowy: BOSSBS-5161R-A647
j.m.: 1 * 100 µl
Producent: Bioss


Opis: The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
Numer katalogowy: BOSSBS-13343R-HRP
j.m.: 1 * 100 µl
Producent: Bioss


Opis: Szkło sodowo-wapniowe.
Numer katalogowy: LENZ05127008
j.m.: 1 * 1 kg
Producent: Lenz Laborglas GmbH & CO.KG


Opis: 2-Propanol-D1, Sigma-Aldrich®
Numer katalogowy: SIAL615080-5G
j.m.: 1 * 5 g
Producent: Merck


Opis: Cyfrowe sondy głębokości z tej serii z wbudowanym czujnikiem barometrycznym i kompensacją temperatury łączą pomiary rozpuszczonego tlenu, pH lub potencjału redox oraz przewodności z dokładnym odczytem głębokości. Można je stosować z jedną, dwoma lub trzema elektrodami IDS. Do pomiarów wymagany jest miernik wieloparametrowy Multi 3430 lub Multi 3630 IDS.
Numer katalogowy: 665-0357
j.m.: 1 * 1 SZT
Producent: WTW


Opis: Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesised MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.
Numer katalogowy: BOSSBS-8481R-A750
j.m.: 1 * 100 µl
Producent: Bioss


Opis: Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.
Numer katalogowy: BOSSBS-8481R-CY3
j.m.: 1 * 100 µl
Producent: Bioss


Opis: Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost.
Numer katalogowy: BOSSBS-10433R
j.m.: 1 * 100 µl
Producent: Bioss


Opis: Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost.
Numer katalogowy: BOSSBS-10433R-CY7
j.m.: 1 * 100 µl
Producent: Bioss


Opis: Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.
Numer katalogowy: BOSSBS-8481R-A647
j.m.: 1 * 100 µl
Producent: Bioss


Opis: Etanol-D1, Sigma-Aldrich®
Numer katalogowy: SIAL151904-25G
j.m.: 1 * 25 g
Producent: Merck


Opis: Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate Signalling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost.
Numer katalogowy: BOSSBS-10433R-A750
j.m.: 1 * 100 µl
Producent: Bioss


Opis: Gamma-aminobutyric acid (GABA) receptors are pentameric membrane proteins that operate GABA-gated chloride channels and inhibit neurotransmission in the central nervous system. The rho receptor subunits do not exhibit sensitivity to typical GABA receptor modulators such as bicuculline, hexobarbital, and diazepam. While the rho 1 subunit localizes specifically to the retina, rho 2 expresses in all regions of the brain, though levels were still highest in the retina, implying a role for both subunits in visual pathways.
Numer katalogowy: BOSSBS-12085R-CY7
j.m.: 1 * 100 µl
Producent: Bioss


Opis: ImmunoReagents’ Biotinylated antibody conjugates are widely used due to their ability to enhance antibody signal in most immunoassays. Biotinylated secondary antibodies are used in most immunoassay formats (i.e., ELISA, Immunohistochemistry (IHC), and Western blotting). While Biotinylated antibodies by themselves do not produce a signal that can be visualized, biotin has a high affinity and specificity to Streptavidin/Avidin. Using ImmunoReagents’ streptavidin conjugates with biotinylated antibodies results in signal amplification.
Numer katalogowy: IMMRIR1301
j.m.: 1 * 2 mg
Producent: ImmunoReagents


Opis: ImmunoReagents’ Biotinylated antibody conjugates are widely used due to their ability to enhance antibody signal in most immunoassays. Biotinylated secondary antibodies are used in most immunoassay formats (i.e., ELISA, Immunohistochemistry (IHC), and Western blotting). While Biotinylated antibodies by themselves do not produce a signal that can be visualized, biotin has a high affinity and specificity to Streptavidin/Avidin. Using ImmunoReagents’ streptavidin conjugates with biotinylated antibodies results in signal amplification.
Numer katalogowy: IMMRIR1468
j.m.: 1 * 1 mg
Producent: ImmunoReagents


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