Wyszukano: Białka

Numer katalogowy: (PRSI91-838)

Producent: ProSci Inc.

Opis: ADAM DEC1 protein is expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. ADAM DEC1 is induced during DC maturation and up-regulated in response to T-cell signals. It may play an important role in the control of the immune response and during pregnancy.

j.m.: 1 * 0,05 mg

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Producent: ENZO LIFE SCIENCES

Opis: MG-132 is a potent, cell permeable and selective proteasome inhibitor (Ki = 4 nM).1 It inhibits NF-κB activation by preventing IκB degradation (IC50 = 3 μM). The peptide blocks degradation of short-lived proteins, which in turn induces HSP and ER chaperone expression, leading to thermotolerance (1 μM MG-132, 2 h.). It also stimulates neurite outgrowth in PC12 cells (20 nM optimal). The peptide has also been reported to increase the survival rate of mesenchymal stem cells following their transplantation. IC50’s for inhibition of Suc-LLVY-AMC and Z-LLL-AMC cleaving activities of proteasome were 0,85 and 0,1 μM respectively. The ubiquitin-proteasome system (UPS) and autophagy serve as two complementary, reciprocally regulated protein degradation systems, thus blockade of UPS by MG-132 activates autophagy.

New Product

Numer katalogowy: (ENZOBMLG4200001)

Producent: ENZO LIFE SCIENCES

Opis: Phospholipase activator

j.m.: 1 * 1 mg

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Numer katalogowy: (ENZOBMLG4450001)

Producent: ENZO LIFE SCIENCES

Opis: Ultra-pure

j.m.: 1 * 1 mg

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Numer katalogowy: (SHBTPB-500-10)

Producent: Shenandoah Biotechnology

Opis: Cytokines for polarizing T cells into T regulatory cells. T regulatory cells (Tregs) are a subset of T cells that suppress immune function. They are characterized by the expression of CD4, CD25 and Foxp3 and are known to produce immunosuppressive cytokines TGF-β 1 and IL-10. Tregs can be cultured from naive CD4+ T cells by culturing them in the presence of IL-2 and TGF-β 1 with CD3 and CD28 stimulation. In some cases cells are also cultured with neutralizing antibodies to IL-4, IFNγ and IL-12 and/or retinoic acid.

j.m.: 1 * 1 KIT

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Numer katalogowy: (SHBTPB-500-03)

Producent: Shenandoah Biotechnology

Opis: Cytokines for expansion and cell culture of human hematopoietic stem cells. Hematopoietic stem cells are self renewing pluripotent cells often characterised by the expression of CD34. Studies have shown that decreased expression of CD34 tends to correlate with decreased self renewal properties and pluripotent potential. Culturing CD34+ cells in a cytokine mixture of TPO, SCF, and FLT-3 Ligand for short time periods allows CD34+ cells to proliferate without decreasing CD34 expression, thus retaining their stem cell properties. The combination of these cytokines allows for the <i>ex vivo</i> expansion of the most immature hematopoietic stem cells in cord blood or bone marrow preparations, but can be supplemented with other cytokines to promote specific lineages. For example, GM-CSF and/or G-CSF can be added to promote monocytes and granulocytes while EPO can be added to promote erthroid cells.

j.m.: 1 * 1 KIT

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Numer katalogowy: (ENZOALX157011MC01)

Producent: ENZO LIFE SCIENCES

Opis: Guanylyl cyclase activator

j.m.: 1 * 0,1 mg

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Producent: ENZO LIFE SCIENCES

Opis: Human;Pig;Rat Endothelin 3

New Product

Numer katalogowy: (ENZOALX155023M001)

Producent: ENZO LIFE SCIENCES

Opis: Specific PKC substrate

j.m.: 1 * 1 mg

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Numer katalogowy: (ENZOALX521005C005)

Producent: ENZO LIFE SCIENCES

Opis: Produced in <i>E. coli</i>. Dimer of two identical subunits (119 aa) linked together by very strong hydrophobic interactions.

j.m.: 1 * 5 µG

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Numer katalogowy: (ENZOALX522002C050)

Producent: ENZO LIFE SCIENCES

Opis: Produced in HEK 293 cells. The extracellular domain of human Fas (CD95; APO-1) (aa 7-154) is fused to the Fc portion of human IgG1.

j.m.: 1 * 50 µG

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Producent: Shenandoah Biotechnology

Opis: Neutrophil activating peptide 2 (NAP-2), also known as CXCL7, is a member of the CXC family of chemokines. NAP-2 is a carboxyl-terminal fragment produced by proteolytic cleavage of the platelet basic protein (PBP). NAP-2 is released from platelets and binds to the receptors CXCR1 and CXCR2 to chemoattract and activate neutrophils during inflammatory events.

New Product

Producent: Shenandoah Biotechnology

Opis: B cell-attracting chemokine 1 (BCA-1), also known as CXCL13, is expressed at high levels in lymphoid tissues, such as the spleen, lymph nodes, and Peyer's patches.  BCA-1 activates signaling through the receptor Burkitt lymphoma receptor 1 (BLR1) to chemoattract B cells.

New Product

Producent: Thermo Fisher Scientific

Opis: CAS No.: 13433-09-5

MSDS

Producent: Biosensis

Opis: Mouse NGF (2.5S) was isolated from mouse submaxillary glands by method of Mobley et al (1976) and is a form of beta-NGF that has identical biological properties. NGF is known to regulate the survival and development of certain sympathetic and sensory neurons. It is a dimer with 2 identical polypeptide chains and dimeric molecular weight of approximately 26,500 Da. Isolation and purification of NGF from mouse submaxillary glands yields preparations of NGF (2.5S) with identical biological activity but with cleavages at the amino terminus (with the loss of 8 amino acids) and/or at the carboxy-terminus (with the loss of arginine). These preparations are named 2.5 NGF.

Certyfikaty

Numer katalogowy: (APOSBITP1753-1MG)

Producent: Apollo Scientific

Opis: Recombinant Hepatitis C Virus Nucleocapsid (core) Genotype-5

j.m.: 1 * 1 mg

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