Drukuj

Pinometostat (EPZ-5676) ≥98%

Dostawca: Cayman Chemical

Synonim: (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(((cis-3-(2-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutyl)(isopropyl)amino)methyl)tetrahydrofuran-3,4-diol, Pinometostat

16175-10 16175-1 16175-25 16175-5
CAYM16175-10EA 2120 PLN
CAYM16175-10 CAYM16175-1 CAYM16175-25 CAYM16175-5
Pinometostat (EPZ-5676) ≥98%
Pinometostat (EPZ-5676)

EPZ5676 is a highly potent aminonucleoside inhibitor of DOT1 l histone methyltransferase activity (Ki = 80 pM) that demonstrates 37000-fold selectivity over other methyltransferases.


It can selectively inhibit the proliferation of acute leukemia cell lines bearing MLL translocations (IC50s range from 3.5 nM - 1.3 µM).

Formuła: C₃₀H₄₂N₈O₃
MW: 562.71 g/mol
Temperatura przechowywania: Zamra·arka
Numer MDL: MFCD24849415
Numer CAS: 1380288-87-8

Zobacz ceny

Wyniki testów specyfikacyjnych

Purity ≥98%
Formulation A Crystalline Solid
λmax 255 nm


Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Więcej About VWR